Ca 2+ ‐regulated cell migration revealed by optogenetically engineered Ca 2+ oscillations
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Ca 2 - stimulated Ca 2 Oscillations Produced by the Ca 2 - sensing Receptor Require Negative Feedback by Protein Kinase
We examined the role of protein kinase C (PKC) in the mechanism and regulation of intracellular Ca concentration ([Ca ]i) oscillations elicited by an increase in the extracellular concentration of Ca ([Ca ]e) in human embryonic kidney 293 cells expressing the Ca sensing receptor (CaR). Exposure to the PKC inhibitors bisindolylmaleimide I (GF I) or Ro-31-8220 converted oscillatory responses to t...
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Confocal laser scanning microscopy and fluo 4 were used to visualize local and whole cell Ca(2+) transients within individual smooth muscle cells (SMC) of intact, pressurized rat mesenteric small arteries during activation of alpha1-adrenoceptors. A method was developed to record the Ca(2+) transients within individual SMC during the changes in arterial diameter. Three distinct types of "Ca(2+)...
متن کاملAdrenergic stimulation of rat resistance arteries affects Ca 2 1 sparks , Ca 2 1 waves , and Ca 2 1 oscillations
Mauban, Joseph R. H., Christine Lamont, C. William Balke, and W. Gil Wier. Adrenergic stimulation of rat resistance arteries affects Ca21 sparks, Ca21 waves, and Ca21 oscillations. Am J Physiol Heart Circ Physiol 280: H2399–H2405, 2001.—Confocal laser scanning microscopy and fluo 4 were used to visualize local and whole cell Ca21 transients within individual smooth muscle cells (SMC) of intact,...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 2020
ISSN: 0021-9541,1097-4652
DOI: 10.1002/jcp.30190